Mephedrone FAQ

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1. What is Mephedrone?
Mephedrone, 4-Methylmethcathinone, is a potent CNS stimulant and empathogen. It is dopaminergic and most likely somewhat serotonergic. It is a white powder with a pungent odor that originated in Israel around 2007.

2. How is it taken?
Mephedrone is generally swallowed and/or insufflated.

3. What does it do?
It produces great CNS stimulation, dry mouth, increased perspiration, decreased appetite, very dilated pupils, occasional jaw tension and GI discomfort. It produces euphoric and empathetic feelings, both hardening and softening the ego, along with an impaired short term memory. It can also produces sores in the mouth and cause knees and elbows to turn slightly blue due to severe vasoconstriction. It is suspected to be both neuro and cardiotoxic.

4. How long does it last?
Mephedrone typically lasts 2-2.5 hours when taken orally, 1-2 hours when insufflated, 1 hour when IVed, and 1-2 hours when administered rectally.

5. How much is needed for a dose?
Orally: 200-300mg insufflated: 100-200mg IV: 75-100mg recatally: 75-100mg

6. Is it dangerous?
Yes, people have reported blue knees and elbows from vasoconstriction. It may be harmful to the brain and heart as well as irritating to mucous membranes when insufflated. Few people have died; however, some others have gotten severely ill after their first dose.

7. Is it addictive?
Mephedrone does not appear to cause physical dependence, though the compulsion to re-dose is intense. Few instances of psychological dependency have been noted; for the most part, once one has not had Mephedrone for 24-48 hours, the cravings severely diminish in presence. Despite this, many people have been addicted to mephedrone.

8. What is particularly harmful to mix with Mephedrone?
Stimulants are most dangerous, but not too much is known about combining Mephedrone with other drugs.

9. What are some beneficial supplements one can take to combat Mephedrone's detrimental health effects?
Tyrosine, Garlic and other vasodilators, Milk, and Fish Oils have been shown most effective thus far.

10. What happens during an overdose?
The user's heartrate will skyrocket and body temperature will increase. Certain places on extremities may turn blue and one may have difficulty breathing or moving.